Chair: Prof. Andrea Maier
8:00 AM – Registration
9:00 AM – Opening Remarks
Prof Andrea Maier - Director - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
9:05 AM – Guest of Honour
Prof Raymond Chua - CEO - Health Sciences Authority
9:15 AM – Cross-tissue molecules of healthy ageing
Prof Nir Eynon - Professor - Monash University
9:40 AM – Computational approaches to measure and target aging
Asso/Prof Morten Scheibye-Knudsen - Associate Professor - University of Copenhagen
10:05 AM – NAD+ metabolism modulation for age-associated diseases: "old" pathways as new targets for healthy longevity
Asst/Prof Vincenzo Sorrentino - Assistant Professor - Yong Loo Lin School of Medicine, NUS
10:35 AM – The effect of nutraceuticals on cellular senescence in animal models and humans
Dr Lihuan Guan - Research Fellow - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
10:45 AM – Bioactive compounds in health and disease
Prof Vasso Apostolopoulos - Head of the Healthy Lifespan and Chronic Diseases Program - RMIT University
11:10 AM – Oral Poster: Okra seed extracts mitigate skin photoaging
Dr Leo Chen Huei- Senior Lecturer - A*STAR Skin Research Labs
11:20 AM – Urolithin A in healthy longevity and brain resilience and the 1st clinical trial for Alzheimer’s disease
Asso/Prof Evandro Fei Fang - Associate Professor - University of Oslo
11:45 AM – Live Beyond: Father and Son Quest for Longevity
5 Minutes Video by Mr Marek Piotrowski (LiveBeyond.world)
12:00 PM – Lunch break
Chair: Prof. Hans Meij
13:00 PM – Off label use of sodium-glucose cotransproter-2 (SGLT2) inhibitor as potential gerotherpeutics in humans: A systematic review
Mr Christian Sotelo - Research Assistant - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
13:05 PM – Metabolic drugs as gerotherapeutics: Repurposing GLP-1 receptor agonists and SGLT2 inhibitors for dementia
Assoc/Prof Sandra Aleksic - Associate Professor - Albert Einstein College of Medicine
13:35 PM – Oral Poster: The FDA-approved drug Ozempic enhances healthy longevity in Caenorhabditis elegans via neuronal mTOR inhibition
Mr Wang Qingyun - PhD Student - Yong Loo Lin School of Medicine, NUS
13:45 PM – Oral Poster: Repurposing anti-psychotics as brain-penetrant TFEB activators to enhance autophagy, cellular resilience, and longevity
Ms Grace Keh - Research Assistant - Yong Loo Lin School of Medicine, NUS
13:55 PM - Poster presentation: 1-min lightning talk competition
Poster presenters
14:20 PM - Afternoon Tea
14:50 PM – Gerotherapeutics in precision geromedicine
Prof Andrea Maier - Director - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
15:10 PM – Who is interested in longevity medicine? Insights from the HELO survey
Dr Jordi Morwani - Research Fellow - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
15:15 PM – Integrating biomarkers of ageing into supplement prescribing
Ms Denise Teo - Senior Dietitian - Chi Longevity
15:30 PM – Optimising healthspan - A healthy longevity research clinic case report
Dr Grace Chiang - Consultant - Alexandra Hospital, NUHS
15:45 PM – Hormone therapy utilised as a geroprotective approach
Dr Tashiya Mirando - British Family Physician - Osler Health
16:00 PM – Menopause as a geroprotection window: midlife women, ageing trajectories and translational evidence
Ms Diana Tan - Founder & CEO - Advocates - Menopause Care Alliance
16:15 PM – Panel 1: How longevity clinic utilise nutraceuticals and repurposed drugs
Moderator: Prof Hans Meij - Co-founder - NUS Academy for Healthy Longevity
Prof José María Valderas - Director of the Centre for Research in Health Systems Performance & Head of the Department of Family Medicine - Yong Loo Lin School of Medicine, NUS
Dr Eu Leong Oh - Resident Physician - Chi Longevity
Dr Neil Forrest - Medical Director - Osler Health
Dr Wanviput Sanphasitvong - Medical Doctor - Bumrungrad Hospital
17:00 PM - Startup pitch competition & Flash Pitch
17:55 PM - Reception/Networking/industry showcase
Chair: Prof Andrea Maier
8:30 AM – Registration
9:00 AM – Recap
Prof Andrea Maier - Director - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
9:05 AM – Ergothioneine – recent developments
Prof Barry Halliwell - Distinguished Professor - Yong Loo Lin School of Medicine, NUS
9:25 AM – Is ergothioneine a “longevity vitamin” that can help unlock healthy ageing?
Prof Bob Beelman - Professor - Penn State University
9:45 AM – Progress in food biomarker studies among Chinese
Prof Geng Zong - Professor - Fudan University
10:05 AM – Ergothioneine industrial manufacturing process
Mr Lin Yi - CEO - Abinopharm, Inc.
10:20 AM – Panel 2: The future of ergothioneine in science, medicine and industry
Moderator: Prof Barry Halliwell - Professor - Yong Loo Lin School of Medicine, NUS
Prof Bob Beelman - Professor - Penn State University
Prof Geng Zong - Professor - Fudan University
Mr Lin Yi - CEO - Abinopharm, Inc.
10:45 AM – Oral Poster: A tiny molecule derived from colourful fruit works as mitochondrial guardian mitigates Alzheimer’s disease pathology
Dr Cao Shuqin - Research Fellow - University of Oslo and Akershus University Hospital
10:55 AM – Start-up pitch competition & Flash Pitch
11:45 AM – Lunch break
Chair: Prof Hans Meij
12:45 PM – Iatrogenic ageing induced by benzodiazepines and glucocorticoids
Prof Guido Kroemer - Professor - Université de Paris Cité, Sorbonne Université
13:10 PM – Precision geromedicine: tailored healthy ageing with lifestyle, supplements, and drugs: A clinical trial
Dr Mazzarine Dotou - Research Fellow - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
13:15 PM – The science of longevity: An integrative approach to extend skin healthspan
Dr Magali Moreau - AVP Scientific Direction, Advanced Research - L’Oréal USA
13:35 PM – Oral Poster: The safety and efficacy of alpha-ketoglutarate supplementation on biological DNA methylation age and mechanisms of ageing in middle-aged healthy adults: ABLE
Dr Weilan Wang - Senior Research Fellow - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
13:45 PM – Microbiome in adulthood: A key to extended healthspan
Dr Christophe Lay - Senior Team Leader - Danone
14:05 PM - Poster presentation: 1-min lightning talk competition
Poster presenters
14:30 PM – Beyond hype: Validating nutraceuticals & repurposed drugs in longevity clinics
Ms Manjit Sareen - Head - Longevity Clinics World
14:45 PM – How to advance gerotherapeutics
Dr Lars Hartenstein - Director - McKinsey Health Institute
15:00 PM – Panel 3: Networks and investment for accelerating evidence-based precision geromedicine
Moderator: Prof Andrea Maier - Director - NUS Academy for Healthy Longevity
Allen Law - CEO - MORROW
Dr Tim Shi - President - Asia-Pacific Longevity Medicine Society
Dr Shamandree Govender - Chief Medical Operations Officer - Chi Longevity
15:40 PM - Afternoon Tea
16:10 PM – Beyond risk protection: the intersection of health and financial planning
Mr Harpreet Bindra - CEO - HSBC Life
16:20 PM – Introducing precision geromedicine into the clinic: Ethical considerations
Asso/Prof Michael Dunn - Co-Director of Education - Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, NUS
16:40 PM – Supplement safety from a toxicology and regulatory perspective
Dr Dushani L. Palliyaguru - CEO - HealthSurveil LC
17:00 PM – Panel 4: Ethical, regulatory, and implementation pathways for geroprotective interventions
Moderator: Prof Hans Meij - Co-founder - NUS Academy for Healthy Longevity
Mr Henry Kwek - Member of Parliment
Prof Paul Anantharajah Tambyah - Senior Consultant - NUHS
Dr Lars Hartenstein - Director - McKinsey Health Institute
Mr Marek Piotrowski - Founder - LiveBeyond.world
17:35 AM – Live Beyond: Father and Son Quest for Longevity
Video by Mr Marek Piotrowski (LiveBeyond.world)
17:40 PM - Award ceremony & Closing speech
Prof Andrea Maier - Director - NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, NUS
